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Jun Zhao Selected Research

Tyrosine Kinase Inhibitors

1/2023Genomic characterisation of de novo EGFR copy number gain and its impact on the efficacy of first-line EGFR-tyrosine kinase inhibitors for EGFR mutated non-small cell lung cancer.
12/2022Prevention of variceal rebleeding in cirrhotic patients with advanced hepatocellular carcinoma receiving molecularly targeted therapy: a randomized pilot study of transjugular intrahepatic portosystemic shunt versus endoscopic plus β-blocker.
4/2022Biomarker subset analysis of a phase IIIb, open-label study of afatinib in EGFR tyrosine kinase inhibitor-naive patients with EGFRm+ non-small-cell lung cancer.
1/2021Predicting Tyrosine Kinase Inhibitor Treatment Response in Stage IV Lung Adenocarcinoma Patients With EGFR Mutation Using Model-Based Deep Transfer Learning.
1/2020Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation.
1/2020Next-generation sequencing based mutation profiling reveals heterogeneity of clinical response and resistance to osimertinib.
9/2019Identifying EGFR mutations in lung adenocarcinoma by noninvasive imaging using radiomics features and random forest modeling.
12/2018Identifying epidermal growth factor receptor mutation status in patients with lung adenocarcinoma by three-dimensional convolutional neural networks.
11/2018Real-world EGFR testing in patients with stage IIIB/IV non-small-cell lung cancer in North China: A multicenter, non-interventional study.
10/2018Mechanisms of primary resistance to EGFR targeted therapy in advanced lung adenocarcinomas.
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Jun Zhao Research Topics

Disease

401Neoplasms (Cancer)
05/2024 - 08/2003
130Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2024 - 11/2005
83Infections
06/2024 - 09/2002
71Neoplasm Metastasis (Metastasis)
02/2024 - 11/2004
58Lung Neoplasms (Lung Cancer)
01/2024 - 04/2007
39Carcinogenesis
02/2024 - 06/2007
37Adenocarcinoma of Lung
01/2024 - 05/2015
35Inflammation (Inflammations)
02/2024 - 06/2006
31Hepatocellular Carcinoma (Hepatoma)
04/2024 - 11/2009
30Adenocarcinoma
03/2024 - 02/2004
28Prostatic Neoplasms (Prostate Cancer)
01/2024 - 02/2003
25Fibrosis (Cirrhosis)
04/2024 - 01/2007
25Pain (Aches)
01/2024 - 07/2006
22Alzheimer Disease (Alzheimer's Disease)
04/2024 - 01/2007
22Stomach Neoplasms (Stomach Cancer)
10/2023 - 06/2005
21COVID-19
07/2023 - 01/2020
20Wounds and Injuries (Trauma)
04/2024 - 01/2013
20Disease Progression
02/2024 - 08/2003
19Cognitive Dysfunction
04/2024 - 03/2014
18Breast Neoplasms (Breast Cancer)
12/2023 - 09/2009
18Colorectal Neoplasms (Colorectal Cancer)
11/2023 - 12/2003
17Small Cell Lung Carcinoma (Small Cell Lung Cancer)
03/2024 - 06/2011
17Carcinoma (Carcinomatosis)
05/2023 - 02/2004
16Pancreatic Neoplasms (Pancreatic Cancer)
04/2024 - 06/2015
16Schizophrenia (Dementia Praecox)
03/2024 - 11/2009
16Renal Cell Carcinoma (Grawitz Tumor)
07/2023 - 09/2006
15Hemorrhage
04/2024 - 08/2008
15Virus Diseases (Viral Diseases)
01/2024 - 11/2013
14Urinary Bladder Neoplasms (Bladder Cancer)
01/2023 - 08/2003
13Hypertension (High Blood Pressure)
02/2024 - 01/2013
13Rectal Neoplasms (Rectal Cancer)
01/2023 - 11/2010
12Hypoxia (Hypoxemia)
02/2024 - 12/2012
12Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2024 - 08/2015
12Liver Neoplasms (Liver Cancer)
11/2023 - 11/2012
12Lymphatic Metastasis
02/2023 - 12/2003
11Liver Cirrhosis (Hepatic Cirrhosis)
11/2023 - 11/2009
11Stroke (Strokes)
02/2023 - 05/2012
11Melanoma (Melanoma, Malignant)
11/2022 - 12/2007
11Esophageal Neoplasms (Esophageal Cancer)
01/2021 - 03/2013
10Fatigue
01/2024 - 02/2016
10Sarcoma (Soft Tissue Sarcoma)
01/2024 - 05/2015
10Gestational Trophoblastic Disease (Trophoblastic Neoplasms, Gestational)
08/2023 - 05/2018
10Neurodegenerative Diseases (Neurodegenerative Disease)
01/2023 - 01/2007
10Ischemic Stroke
01/2023 - 10/2013
10Necrosis
12/2022 - 01/2006
9Type 2 Diabetes Mellitus (MODY)
04/2024 - 02/2013

Drug/Important Bio-Agent (IBA)

109Proteins (Proteins, Gene)FDA Link
04/2024 - 09/2002
61Biomarkers (Surrogate Marker)IBA
03/2024 - 08/2008
38MicroRNAs (MicroRNA)IBA
02/2023 - 01/2011
36DNA (Deoxyribonucleic Acid)IBA
03/2024 - 06/2005
35ErbB Receptors (EGF Receptor)IBA
01/2023 - 12/2008
34Messenger RNA (mRNA)IBA
01/2024 - 10/2003
32CytokinesIBA
10/2023 - 01/2007
30Tyrosine Kinase InhibitorsIBA
01/2023 - 06/2009
29RNA (Ribonucleic Acid)IBA
09/2023 - 09/2006
26Long Noncoding RNAIBA
01/2023 - 07/2016
25VaccinesIBA
02/2023 - 12/2008
24Immune Checkpoint InhibitorsIBA
05/2024 - 01/2018
23Therapeutic UsesIBA
04/2024 - 06/2002
21Phosphotransferases (Kinase)IBA
04/2024 - 06/2009
21Antiviral Agents (Antivirals)IBA
01/2024 - 08/2003
20Interleukin-6 (Interleukin 6)IBA
01/2024 - 08/2003
19AntigensIBA
09/2023 - 12/2003
19LigandsIBA
01/2023 - 11/2006
18PlatinumIBA
03/2024 - 06/2008
17EnzymesIBA
12/2023 - 06/2006
17AntibodiesIBA
01/2023 - 08/2003
16Amyloid (Amyloid Fibrils)IBA
04/2024 - 09/2011
16Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
04/2024 - 11/2004
16InterferonsIBA
03/2024 - 12/2012
16asenapineFDA Link
06/2015 - 11/2009
14Peptides (Polypeptides)IBA
01/2024 - 01/2006
13Olanzapine (Zyprexa)FDA Link
07/2022 - 12/2009
13Small Interfering RNA (siRNA)IBA
09/2020 - 12/2007
12Reactive Oxygen Species (Oxygen Radicals)IBA
11/2023 - 10/2011
12CateninsIBA
01/2023 - 10/2016
12apatinibIBA
01/2023 - 09/2017
11Cisplatin (Platino)FDA LinkGeneric
11/2022 - 03/2014
10Circular RNAIBA
01/2024 - 01/2018
10Caspase 3 (Caspase-3)IBA
12/2022 - 10/2011
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2018 - 11/2005
9hydroxide ionIBA
04/2024 - 03/2010
9SteroidsIBA
03/2024 - 11/2017
9SolutionsIBA
03/2024 - 08/2008
9Glucose (Dextrose)FDA LinkGeneric
03/2024 - 05/2004
9CrizotinibIBA
02/2024 - 10/2015
9Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2024 - 08/2003
9AntioxidantsIBA
01/2024 - 01/2013
9B7-H1 AntigenIBA
11/2023 - 01/2018

Therapy/Procedure

167Therapeutics
04/2024 - 10/2003
110Drug Therapy (Chemotherapy)
02/2024 - 12/2006
43Immunotherapy
03/2024 - 03/2006
37Radiotherapy
11/2023 - 11/2004
13Aftercare (After-Treatment)
04/2024 - 10/2013
13Lasers (Laser)
04/2024 - 06/2011
13Neoadjuvant Therapy
12/2023 - 11/2010
11Chinese Traditional Medicine (Traditional Chinese Medicine)
03/2024 - 10/2011
10Length of Stay
04/2024 - 03/2013
10Transplantation
04/2024 - 01/2012
9Lymph Node Excision (Lymph Node Dissection)
09/2023 - 09/2013